Neural circuitry and plasticity mechanisms underlying delay eyeblink conditioning
نویسندگان
چکیده
منابع مشابه
The neural circuitry and molecular mechanisms underlying delay and trace eyeblink conditioning in mice.
Classical eyeblink conditioning (EBC), a simple form of associative learning, has long been served as a model for motor learning and modulation. The neural circuitry of EBC has been studied in detail in rabbits. However, its underlying molecular mechanisms remain unclear. The advent of mouse transgenics has generated new perspectives on the studies of the neural substrates and molecular mechani...
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Classical conditioning paradigms, such as trace conditioning, in which a silent period elapses between the offset of the conditioned stimulus (CS) and the delivery of the unconditioned stimulus (US), and delay conditioning, in which the CS and US coterminate, are widely used to study the neural substrates of associative learning. However, there are significant gaps in our knowledge of the neura...
متن کاملEyeblink classical conditioning in H.M.: delay and trace paradigms.
H.M., a well-known subject with bilateral removal of medial-temporal-lobe structures and profound amnesia, performed eyeblink classical conditioning (EBCC) for 21 90-trial sessions in the 400-ms delay and 900-ms trace paradigms. A 2nd amnesic subject with temporal lobe lesions and 2 normal control subjects (NCSs) were also conditioned. Acquisition occurred in both paradigms for all subjects. Ac...
متن کاملParallel acquisition of awareness and differential delay eyeblink conditioning.
There is considerable debate about whether differential delay eyeblink conditioning can be acquired without awareness of the stimulus contingencies. Previous investigations of the relationship between differential-delay eyeblink conditioning and awareness of the stimulus contingencies have assessed awareness after the conditioning session was finished using a post-experimental questionnaire. In...
متن کاملStandard delay eyeblink classical conditioning is independent of awareness.
P. F. Lovibond and D. R. Shanks (2002) suggested that all forms of classical conditioning depend on awareness of the stimulus contingencies. This article considers the available data for eyeblink classical conditioning, including data from 2 studies (R. E. Clark, J. R. Manns, & L. R. Squire, 2001; J. R. Manns, R. E. Clark, & L. R. Squire, 2001) that were completed too recently to have been cons...
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ژورنال
عنوان ژورنال: Learning & Memory
سال: 2011
ISSN: 1072-0502,1549-5485
DOI: 10.1101/lm.2023011